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New Alliances at a Glance

Alliances At-A-Glance

To achieve our goals of bringing safe and effective medicines to patients in need, as well as achieving long-term growth, Daiichi Sankyo partners with a variety of organizations to focus on progressing promising products that complement our in-house portfolio.

Our strategy involves in-licensing new products and product candidates, acquiring companies that will drive our portfolio in key therapeutic areas, as well as partnering on specific aspects of research, development and/or commercialization.

Our decades-long history of effective collaboration exemplifies our ability to license products in and out of Daiichi Sankyo, develop and maintain valuable partnerships, and successfully complete mergers and acquisitions.

Here is a snapshot of our activity:

2018 Glycotope

An exclusive worldwide licensing agreement to develop an antibody drug conjugate (ADC) by combining Daiichi Sankyos proprietary ADC technology with Glycotope’s investigational tumor-associated TA-MUC1 antibody gatipotuzumab (formerly PankoMab-GEX®) building on a previous 2017 option agreement.

2018 DarwinHealth A research agreement  for novel cancer target initiative database in order to identify potential new targets for cancer drug development
2018 Zymeworks, Inc

A licensing agreement to acquire licenses to ZymeworksAzymetric™ and EFECT™ technologies to develop two additional bispecific antibodies building on previous 2016 cross-licensing and collaboration agreement

2018 Merck & Co., Inc. A clinical trial collaboration agreement to evaluate the combination of Daiichi Sankyo’s investigational HER2 targeting antibody drug conjugate DS-8201 and KEYTRUDA® (pembrolizumab) in HER2 expressing advanced/metastatic breast and HER2 expressing or HER2 mutant non-small cell lung cancers (NSCLC).
2017 Puma Biotechnology A preclinical research collaboration with Puma Biotechnology, Inc.
and Memorial Sloan Kettering Cancer Center in HER2-mutated cancer or HER2-positive solid tumors.

2017

MD Anderson Cancer Center

A research collaboration focused on accelerating
the development of novel therapies for acute myeloid leukemia (AML)

2017

Bristol-Myers Squibb

A research collaboration to evaluate Opdivo® (nivolumab) and DS-8201 in HER2-expressing breast and bladder cancers

2017

Max Planck Innovation GmbH and Lead Discovery Center GmbH

An agreement between Daiichi Sankyo, Max Planck Innovation and the Lead Discovery Center providing Daiichi Sankyo with the option to receive the exclusive rights to a new lead compound for the treatment of cancer to be discovered and developed at the Lead Discovery Center

2017

Heptares Therapeutics, the wholly owned subsidiary of Sosei Group Corporation

A drug discovery and licensing agreement with Heptares Therapeutics, part of the Sosei Group, that is focused on a single G protein-coupled receptor (GPCR) that plays a crucial role in relieving pain

2017

Kite Pharma

A strategic partnership with Kite Pharma, a subsidiary of Gilead Sciences, Inc.,  for the exclusive rights of development, manufacturing and commercialization in Japan of Kite’s cellular cancer therapy axicabtagene ciloleucel (KTE-C19)

2016

Amgen

An exclusive agreement to commercialize nine biosimilars in Japan, including several biosimilars in late stage development, including biosimilars of adalimumab, bevacizumab and trastuzumab

2016

Celixir

An agreement  with Celixir for an exclusive license in Japan to develop and market Heartcel™, an immune-modulatory progenitor (iMP) cell therapeutic agent for ischemic heart failure currently in development

2016

AgonOx, Inc.

A strategic collaboration with AgonOx, Inc. to develop an undisclosed immuno-oncology target

2016

Inspirion Delivery Sciences

A  collaboration to commercialize two abuse-deterrent opioid medications, MorphaBond™ ER and RoxyBond™, both of which feature a unique, patent-protected abuse-deterrent technology

2015

AstraZeneca

A co-commercialization agreement for Movantik®, a medication indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain

2014

Sanford-Burnham Medical Research Institute

A comprehensive alliance to develop first-in-class therapeutics for the treatment of cardiovascular-metabolic diseases. The collaboration is built on an open-innovation model to bridge the gap between target discovery and pre-clinical drug development.

2014

Virtici, LLC and Celdara Medical, LLC

A collaboration to jointly investigate novel therapeutic candidates and thereby further strengthen the Daiichi Sankyo developmental pipeline across multiple therapeutic areas

2014

University of California, San Francisco

A drug discovery collaboration focused on developing novel therapeutics and molecular diagnostics for multiple neurodegenerative diseases

Note: This is not a complete list of Daiichi Sankyo alliances

PP-US-NP-0276 09/2017

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